WDYHV1 Antibody, HRP conjugated

Code CSB-PA850306LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) WDYHV1 Polyclonal antibody
Uniprot No.
Target Names
WDYHV1
Alternative Names
WDYHV1 antibody; C8orf32 antibody; NTAQ1 antibody; Protein N-terminal glutamine amidohydrolase antibody; EC 3.5.1.122 antibody; Protein NH2-terminal glutamine deamidase antibody; N-terminal Gln amidase antibody; Nt(Q)-amidase antibody; WDYHV motif-containing protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein N-terminal glutamine amidohydrolase protein (1-205AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
Gene References into Functions
  1. the peptide backbone recognition patch of hNtaq1 forms nonspecific interactions with N-terminal peptides of substrate proteins PMID: 25356641
Subcellular Location
Cytoplasm, cytosol. Nucleus.
Protein Families
NTAQ1 family
Database Links

HGNC: 25490

KEGG: hsa:55093

STRING: 9606.ENSP00000287387

UniGene: Hs.18029

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